stannous sulfate

Sodium isethionate: specs, sourcing, and the real-world story behind a quiet workhorse If you formulate cleansers or fabric auxiliaries, you’ve probably run into sodium isethionate at some point—maybe without even noticing. It’s not the flashy surfactant headliner; it’s the steady co‑star that keeps systems soluble, stable, and mild. I’ve watched this ingredient go from “nice-to-have” to “quietly essential” in a decade of lab visits, particularly in sulfate‑free projects and in syndet bar lines trying to juggle hardness, mildness, and processability. What it is (and what it isn’t) Synonyms: Isethionic acid, sodium salt; Sodium hydroxyethyl sulfonate. CAS: 1562-00-1. Origin: 2-7-523 Jidong Building Materials, Tangshan, Hebei 064000, China. Worth noting: sodium isethionate is the small, highly water‑soluble salt—not the fatty‑acid derivative (that’s sodium cocoyl isethionate, a surfactant). Here, we’re talking about the clean, neutral helper: hydrotrope, processing aid, and pH‑friendly building block. Typical product specification Parameter Typical value (≈) Method / Standard Assay (dry basis) ≥ 98.0% HPLC (ICH Q2(R1) validated) Moisture ≤ 1.0% Karl Fischer pH (10% aq.) 6.0–8.0 Potentiometric Heavy metals (as Pb) ≤ 10 ppm ICP‑MS (USP <232>/ICH Q3D) Residual EO/EG ND/trace GC‑MS (in‑house, ICH Q2) Appearance White crystalline powder Visual Process flow (lab-to-plant, condensed) Materials: sodium bisulfite + ethylene oxide (EO) or neutralization of isethionic acid with NaOH. Methods: controlled EO addition in aqueous medium at low temp; or acid‑base neutralization. Purification: decolorization → filtration → concentration → crystallization → drying. QC: assay, identity (FTIR/NMR), metals (ICP‑MS), residuals (GC‑MS), microbial counts where applicable (USP <61>/<62>). Typical shelf life ≈ 24 months in sealed PE-lined bags, ≤ 30°C, dry storage. Applications and why formulators use it Personal care: co‑solubilizer/hydrotrope in sulfate‑free shampoos; processing aid with SCI noodles; bar hardness tuning. Many customers say it helps reduce stickiness. Home care: boosts dye/soil solubility in liquid detergents; improves clarity. Textiles & dyeing: leveling aid; helps disperse reactive dyes and reduce spotting. Electroplating/additives: conductivity modifier where mild sulfonates are needed. Trend‑wise, sodium isethionate is riding the “simplify the INCI list” wave—short, readable, and generally well‑tolerated. Not magical, just reliable. Vendor snapshot (real‑world differences) Vendor Assay spec Docs Compliance Lead time Price band Moneidechem (Hebei) ≥ 98% COA, TDS, SDS, method vldn ISO 9001; REACH-ready 7–14 days Mid Global Trader A ≥ 95% Basic COA Unknown 3–5 weeks Low Regional Producer B ≥ 99% COA, SDS ISO 9001 2–3 weeks High Real‑world use may vary: if you’re scaling a syndet bar line, documentation and residual controls often trump a slightly lower price. Customization, packaging, and QC extras Customizable sieve cut (to reduce dusting), moisture targets, and low‑residual grades for sensitive personal‑care builds. Common packs: 25 kg PE‑lined kraft bags or 500 kg FIBC. Batch testing includes HPLC assay and GC‑MS screening; some buyers request additional allergen and nitrosamine checks (belt‑and‑suspenders, but I get it). Mini case notes APAC personal‑care plant: switching to sodium isethionate at 1.5–2.0% as a hydrotrope improved SCI bar extrusion consistency; scrap fell ≈ 12% month‑over‑month. Reactive dye house: adding 0.3% sodium isethionate reduced shade variation on cotton; customer feedback called out “cleaner” liquor and fewer specks. Compliance note: Beauty and detergent uses typically align with IFRA‑irrelevant categories; check local chemical inventories and REACH status. Always patch test in leave‑on systems (rare, but I’ve seen it attempted). References PubChem. Sodium isethionate (CAS 1562‑00‑1). https://pubchem.ncbi.nlm.nih.gov/ OECD SIDS for Isethionic Acid and Salts (screening information data set). https://www.oecd.org/chemicalsafety/ USP General Chapters <232> and ICH Q3D on elemental impurities. https://www.uspnf.com/; https://www.ich.org/ ICH Q2(R1) Validation of Analytical Procedures. https://www.ich.org/